Weak coverage of a rectangular barrier

Assume n wireless mobile sensors are initially dispersed in an ad hoc manner in a rectangular region. They are required to move to final locations so that they can detect any intruder crossing the region in a direction parallel to the sides of the rectangle, and thus provide weak bar-rier coverage of the region. We study three optimization problems related to the movement of sensors to achieve weak barrier coverage: minimizing the number of sensors moved (MinNum), minimizing the average distance moved by the sensors (MinSum), and minimizing the maximum distance moved by the sensors (

Reconstruction of time-consistent species trees

Background The history of gene families—which are equivalent to event-labeled gene trees—can to some extent be reconstructed from empirically estimated evolutionary event-relations containing pairs of orthologous, paralogous or xenologous genes. The question then arises as whether inferred event-labeled gene trees are “biologically feasible” which is the case if one can find a species tree with which the gene tree can be reconciled in a time-consistent way. Results In this contribution, we consider event-labeled gene trees that contain speciations, duplications as well as horizontal gene transfer (HGT) and we assume that the species tree is unknown. Although many problems become NP-hard as soon as HGT and time-consistency are involved, we show, in contrast, that the problem of finding a time-consistent species tree for a given event-labeled gene can be solved in polynomial-time. We provide a cubic-time algorithm to decide whether a “time-consistent” species tree for a given event-labeled gene tree exists and, in the affirmative case, to construct the species tree within the same time-complexity

Weak Coverage of a Rectangular Barrier

Assume n wireless mobile sensors are initially dispersed in an ad hoc manner in a rectangular region. Each sensor can monitor a circular area of specific diameter around its position, called the sensor diameter. Sensors are required to move to final locations so that they can there detect any intruder crossing the region in a direction parallel to the sides of the rectangle, and thus provide weak barrier coverage of the region. We study three optimization problems related to the movement of sensors to achieve weak barrier coverage: minimizing the number of sensors moved (MinNum), minimizing the average distance moved by the sensors (MinSum), and minimizing the maximum distance moved by any sensor (MinMax). We give an O(n3 / 2) time algorithm for the MinNum problem for sensors of diameter 1 that are initially placed at integer positions; in cont

A software tool ‘CroCo’ detects pervasive cross-species contamination in next generation sequencing data

International audienceBackground: Multiple RNA samples are frequently processed together and often mixed before multiplex sequencing in the same sequencing run. While different samples can be separated post sequencing using sample barcodes, the possibility of cross contamination between biological samples from different species that have been processed or sequenced in parallel has the potential to be extremely deleterious for downstream analyses